Center Researcher Published in Journal of Neuropathology and Experimental Neurology
In an article published in the September 2011 edition of The Journal of Neuropathology and Experimental Neurology senior author Dr. Naruhiko Sahara along with contributors from the Mayo Clinic Jacksonville reported that very little caspase-cleaved tau existed in tauopathy mouse model. Our finding suggests that caspase activation might be one of multiple routes during neurodegenerative processes in tauopathies. Caspase, a family of cysteine proteases that play essential roles in apoptosis, has previously been implicated in processes associated with the development of tauopathy.
Click Here for the PubMed abstract for this paper.