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Frontotemporal Lobar Degeneration

Frontotemporal Lobar Degeneration (FTLD)

Frontotemporal Lobar Degeneration (FTLD) is a family of disorders that also included Pick’s Disease and frontotemporal dementia with amyotrophic lateral sclerosis. FTLD is pathologically characterized by damage to the brain cells in the frontal and temporal cortex of the brain (Figure 1). Between the ages of 45-64, approximately 7 people per 100,00 will be affected. A person who develops dementia after the age of 75 would be more likely to Alzheimer’s disease and not frontotemporal dementia.

 

Figure 1: The frontal Cortex of the human brain is shown in blue. The temporal cortex is shown in green.  Nerve cells in these regions are damaged and die in FTLD causing profound changes in thinking and behavior.  Image source- Center for Plain Language.org

Figure 1: The frontal Cortex of the human brain is shown in blue. The temporal cortex is shown in green. Nerve cells in these regions are damaged and die in FTLD causing profound changes in thinking and behavior. Image source- Center for Plain Language.org

For more information on FTLD, click here

FTLD Research at CTRND

Researchers

Dr. Jada Lewis

Dr. Naruhiko Sahara