Cara L Croft

Cara L Croft

Postdoctoral Research Associate

Department: MD-NEUROSCIENCE-GENERAL
Business Phone: (352) 273-9691
Business Email: cara.croft@ufl.edu

Publications

2020
Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene expression in the CNS.
Molecular neurodegeneration. 15(1) [DOI] 10.1186/s13024-020-00361-z. [PMID] 32122372.
2019
rAAV-based brain slice culture models of Alzheimer’s and Parkinson’s disease inclusion pathologies.
The Journal of experimental medicine. 216(3):539-555 [DOI] 10.1084/jem.20182184. [PMID] 30770411.
2019
Organotypic brain slice cultures to model neurodegenerative proteinopathies.
Molecular neurodegeneration. 14(1) [DOI] 10.1186/s13024-019-0346-0. [PMID] 31791377.
2019
An anti-CRF antibody suppresses the HPA axis and reverses stress-induced phenotypes.
The Journal of experimental medicine. 216(11):2479-2491 [DOI] 10.1084/jem.20190430. [PMID] 31467037.
2018
SIRT1: A Novel Way to Target Tau?
The Journal of neuroscience : the official journal of the Society for Neuroscience. 38(36):7755-7757 [DOI] 10.1523/JNEUROSCI.1201-18.2018. [PMID] 30185537.
2018
Preparation of organotypic brain slice cultures for the study of Alzheimer’s disease.
F1000Research. 7 [DOI] 10.12688/f1000research.14500.2. [PMID] 29904599.
2018
Novel monoclonal antibodies targeting the microtubule-binding domain of human tau.
PloS one. 13(4) [DOI] 10.1371/journal.pone.0195211. [PMID] 29608591.
2018
Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies.
The Journal of biological chemistry. 293(12) [DOI] 10.1074/jbc.AAC118.002657. [PMID] 29572329.
2018
Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies.
The Journal of biological chemistry. 293(7):2408-2421 [DOI] 10.1074/jbc.M117.815357. [PMID] 29259137.
2017
Targeting psychologic stress signaling pathways in Alzheimer’s disease.
Molecular neurodegeneration. 12(1) [DOI] 10.1186/s13024-017-0190-z. [PMID] 28633663.
2017
Inhibition of glycogen synthase kinase-3 by BTA-EG4 reduces tau abnormalities in an organotypic brain slice culture model of Alzheimer’s disease.
Scientific reports. 7(1) [DOI] 10.1038/s41598-017-07906-1. [PMID] 28785087.
2017
Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures.
Cell death & disease. 8(3) [DOI] 10.1038/cddis.2017.97. [PMID] 28300838.
2016
Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer’s disease brain.
Acta neuropathologica communications. 4 [DOI] 10.1186/s40478-016-0299-2. [PMID] 27036949.
2015
Constant light enhances synchrony among circadian clock cells and promotes behavioral rhythms in VPAC2-signaling deficient mice.
Scientific reports. 5 [DOI] 10.1038/srep14044. [PMID] 26370467.
2014
Calpain cleavage and inactivation of the sodium calcium exchanger-3 occur downstream of Aβ in Alzheimer’s disease.
Aging cell. 13(1):49-59 [DOI] 10.1111/acel.12148. [PMID] 23919677.
2014
Astrocytes and neuroinflammation in Alzheimer’s disease.
Biochemical Society transactions. 42(5):1321-5 [DOI] 10.1042/BST20140155. [PMID] 25233410.

Grants

Jul 2018 ACTIVE
Understanding and Targeting Tau-induced Neurodegeneration
Role: Principal Investigator
Funding: BRIGHTFOCUS FOU

Teaching Profile

Courses Taught
2018
EGN4912 Engineering Directed Independent Research

Contact Details

Phones:
Business:
(352) 273-9691
Emails:
Business:
cara.croft@ufl.edu