Thomas C Foster

Thomas C Foster

Professor, Evelyn F. McKnight Chair For Research On Cognitive Aging And Memory

Department: MD-NEUROSCIENCE-GENERAL
Business Phone: (352) 273-0033
Business Email: foster1@ufl.edu

Publications

2020
Differential Effect of Repeated Lipopolysaccharide Treatment and Aging on Hippocampal Function and Biomarkers of Hippocampal Senescence.
Molecular neurobiology. 57(10):4045-4059 [DOI] 10.1007/s12035-020-02008-y. [PMID] 32651758.
2020
MicroRNA predicts cognitive performance in healthy older adults.
Neurobiology of aging. 95:186-194 [DOI] 10.1016/j.neurobiolaging.2020.07.023. [PMID] 32846274.
2020
Microglia senescence occurs in both substantia nigra and ventral tegmental area.
Glia. 68(11):2228-2245 [DOI] 10.1002/glia.23834. [PMID] 32275335.
2020
Longitudinal Characterization and Biomarkers of Age and Sex Differences in the Decline of Spatial Memory.
Frontiers in aging neuroscience. 12 [DOI] 10.3389/fnagi.2020.00034. [PMID] 32153384.
2020
Enrichment of genomic pathways based on differential DNA methylation profiles associated with chronic musculoskeletal pain in older adults: An exploratory study.
Molecular pain. 16 [DOI] 10.1177/1744806920966902. [PMID] 33073674.
2020
G Protein-Coupled Estrogen Receptor: Rapid Effects on Hippocampal-Dependent Spatial Memory and Synaptic Plasticity.
Frontiers in endocrinology. 11 [DOI] 10.3389/fendo.2020.00385. [PMID] 32587576.
2020
Hippocampal Subregion Transcriptomic Profiles Reflect Strategy Selection during Cognitive Aging.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 40(25):4888-4899 [DOI] 10.1523/JNEUROSCI.2944-19.2020. [PMID] 32376783.
2019
Age and Sex Influence the Hippocampal Response and Recovery Following Sepsis.
Molecular neurobiology. 56(12):8557-8572 [DOI] 10.1007/s12035-019-01681-y. [PMID] 31278440.
2019
Alteration in NMDA Receptor Mediated Glutamatergic Neurotransmission in the Hippocampus During Senescence.
Neurochemical research. 44(1):38-48 [DOI] 10.1007/s11064-018-2634-4. [PMID] 30209673.
2019
Animal models of cognitive aging and circuit-specific vulnerability.
Handbook of clinical neurology. 167:19-36 [DOI] 10.1016/B978-0-12-804766-8.00002-9. [PMID] 31753133.
2019
Behavior Model for Assessing Decline in Executive Function During Aging and Neurodegenerative Diseases.
Methods in molecular biology (Clifton, N.J.). 2011:441-449 [DOI] 10.1007/978-1-4939-9554-7_26. [PMID] 31273715.
2019
Effect of Systemic Inflammation on Rat Attentional Function and Neuroinflammation: Possible Protective Role for Food Restriction.
Frontiers in aging neuroscience. 11 [DOI] 10.3389/fnagi.2019.00296. [PMID] 31708767.
2019
Enhancement of BDNF Expression and Memory by HDAC Inhibition Requires BET Bromodomain Reader Proteins.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 39(4):612-626 [DOI] 10.1523/JNEUROSCI.1604-18.2018. [PMID] 30504275.
2019
Epigenetic aging is associated with clinical and experimental pain in community-dwelling older adults.
Molecular pain. 15 [DOI] 10.1177/1744806919871819. [PMID] 31394966.
2019
GSTA4 mediates reduction of cisplatin ototoxicity in female mice.
Nature communications. 10(1) [DOI] 10.1038/s41467-019-12073-0. [PMID] 31515474.
2019
How do we validate approaches that aim to harness reserve to improve the aging brain?
Neurobiology of aging. 83:145-149 [DOI] 10.1016/j.neurobiolaging.2019.03.024. [PMID] 31732018.
2019
HSP90 Inhibitor, NVP-AUY922, Improves Myelination in Vitro and Supports the Maintenance of Myelinated Axons in Neuropathic Mice.
ACS chemical neuroscience. 10(6):2890-2902 [DOI] 10.1021/acschemneuro.9b00105. [PMID] 31017387.
2019
Old Mice Demonstrate Organ Dysfunction as well as Prolonged Inflammation, Immunosuppression, and Weight Loss in a Modified Surgical Sepsis Model.
Critical care medicine. 47(11):e919-e929 [DOI] 10.1097/CCM.0000000000003926. [PMID] 31389840.
2019
Senescent neurophysiology: Ca2+ signaling from the membrane to the nucleus.
Neurobiology of learning and memory. 164 [DOI] 10.1016/j.nlm.2019.107064. [PMID] 31394200.
2019
Subunit contribution to NMDA receptor hypofunction and redox sensitivity of hippocampal synaptic transmission during aging.
Aging. 11(14):5140-5157 [DOI] 10.18632/aging.102108. [PMID] 31339863.
2018
Redox Signaling in Neurotransmission and Cognition During Aging.
Antioxidants & redox signaling. 28(18):1724-1745 [DOI] 10.1089/ars.2017.7111. [PMID] 28467718.
2018
Nonsteroidal anti-inflammatory drug, indomethacin improves spatial memory and NMDA receptor function in aged animals.
Neurobiology of aging. 70:184-193 [DOI] 10.1016/j.neurobiolaging.2018.06.026. [PMID] 30031231.
2018
Aging in the Brain: New Roles of Epigenetics in Cognitive Decline.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. 24(5):516-525 [DOI] 10.1177/1073858418780971. [PMID] 29877135.
2017
Central role for NMDA receptors in redox mediated impairment of synaptic function during aging and Alzheimer’s disease.
Behavioural brain research. 322(Pt B):223-232 [DOI] 10.1016/j.bbr.2016.05.012. [PMID] 27180169.
2017
DNA Methylation of Synaptic Genes in the Prefrontal Cortex Is Associated with Aging and Age-Related Cognitive Impairment.
Frontiers in aging neuroscience. 9 [DOI] 10.3389/fnagi.2017.00249. [PMID] 28824413.
2017
Epigenetic regulation of estrogen receptor α contributes to age-related differences in transcription across the hippocampal regions CA1 and CA3.
Neurobiology of aging. 49:79-85 [DOI] 10.1016/j.neurobiolaging.2016.09.013. [PMID] 27776265.
2017
Hippocampal Transcriptomic Profiles: Subfield Vulnerability to Age and Cognitive Impairment.
Frontiers in aging neuroscience. 9 [DOI] 10.3389/fnagi.2017.00383. [PMID] 29276487.
2017
Indomethacin Increases Neurogenesis across Age Groups and Improves Delayed Probe Trial Difference Scores in Middle-Aged Rats.
Frontiers in aging neuroscience. 9 [DOI] 10.3389/fnagi.2017.00280. [PMID] 28928652.
2017
miRNA in Circulating Microvesicles as Biomarkers for Age-Related Cognitive Decline.
Frontiers in aging neuroscience. 9 [DOI] 10.3389/fnagi.2017.00323. [PMID] 29046635.
2016
Increased N-Ethylmaleimide-Sensitive Factor Expression in Amygdala and Perirhinal Cortex during Habituation of Taste Neophobia.
Neural plasticity. 2016 [DOI] 10.1155/2016/2726745. [PMID] 26839712.
2016
Preclinical Magnetic Resonance Imaging and Spectroscopy Studies of Memory, Aging, and Cognitive Decline.
Frontiers in aging neuroscience. 8 [DOI] 10.3389/fnagi.2016.00158. [PMID] 27468264.
2016
Transcription Profile of Aging and Cognition-Related Genes in the Medial Prefrontal Cortex.
Frontiers in aging neuroscience. 8 [DOI] 10.3389/fnagi.2016.00113. [PMID] 27242522.
2016
Type 3 Adenylyl Cyclase and Somatostatin Receptor 3 Expression Persists in Aged Rat Neocortical and Hippocampal Neuronal Cilia.
Frontiers in aging neuroscience. 8 [DOI] 10.3389/fnagi.2016.00127. [PMID] 27303293.
2015
Successful aging: Advancing the science of physical independence in older adults.
Ageing research reviews. 24(Pt B):304-27 [DOI] 10.1016/j.arr.2015.09.005. [PMID] 26462882.
2015
Some hormone, cytokine and chemokine levels that change across lifespan vary by cognitive status in male Fischer 344 rats.
Brain, behavior, and immunity. 49:216-32 [DOI] 10.1016/j.bbi.2015.06.005. [PMID] 26093306.
2015
Re-Opening the Critical Window for Estrogen Therapy.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 35(49):16077-93 [DOI] 10.1523/JNEUROSCI.1890-15.2015. [PMID] 26658861.
2015
Role of estrogen receptor-α on food demand elasticity.
Journal of the experimental analysis of behavior. 103(3):553-61 [DOI] 10.1002/jeab.149. [PMID] 25869426.
2015
Contribution of N-methyl-D-aspartate receptors to attention and episodic spatial memory during senescence.
Neurobiology of learning and memory. 125:36-46 [DOI] 10.1016/j.nlm.2015.07.015. [PMID] 26234588.
2015
Contribution of estrogen receptor subtypes, ERα, ERβ, and GPER1 in rapid estradiol-mediated enhancement of hippocampal synaptic transmission in mice.
Hippocampus. 25(12):1556-66 [DOI] 10.1002/hipo.22475. [PMID] 25980457.
2015
Impaired attention and synaptic senescence of the prefrontal cortex involves redox regulation of NMDA receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 35(9):3966-77 [DOI] 10.1523/JNEUROSCI.3523-14.2015. [PMID] 25740525.
2014
Assessing the emergence and reliability of cognitive decline over the life span in Fisher 344 rats using the spatial water maze.
Frontiers in aging neuroscience. 6 [DOI] 10.3389/fnagi.2014.00002. [PMID] 24478698.
2014
Estrogen receptors, the hippocampus, and memory.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. 20(5):534-45 [DOI] 10.1177/1073858413519865. [PMID] 24510074.
2014
Interaction of DHPG-LTD and synaptic-LTD at senescent CA3-CA1 hippocampal synapses.
Hippocampus. 24(4):466-75 [DOI] 10.1002/hipo.22240. [PMID] 24390964.
2014
Role of antioxidant enzymes in redox regulation of N-methyl-D-aspartate receptor function and memory in middle-aged rats.
Neurobiology of aging. 35(6):1459-68 [DOI] 10.1016/j.neurobiolaging.2013.12.002. [PMID] 24388786.
2013
Role of estrogen receptor α and β in preserving hippocampal function during aging.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(6):2671-83 [DOI] 10.1523/JNEUROSCI.4937-12.2013. [PMID] 23392694.
2013
Memory in aged mice is rescued by enhanced expression of the GluN2B subunit of the NMDA receptor.
Behavioural brain research. 238:211-26 [DOI] 10.1016/j.bbr.2012.10.026. [PMID] 23103326.
2013
Linking redox regulation of NMDAR synaptic function to cognitive decline during aging.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(40):15710-5 [DOI] 10.1523/JNEUROSCI.2176-13.2013. [PMID] 24089479.
2013
Environmental enrichment restores neurogenesis and rapid acquisition in aged rats.
Neurobiology of aging. 34(1):263-74 [DOI] 10.1016/j.neurobiolaging.2012.05.023. [PMID] 22795793.
2013
Daily exercise improves memory, stimulates hippocampal neurogenesis and modulates immune and neuroimmune cytokines in aging rats.
Brain, behavior, and immunity. 28:25-43 [DOI] 10.1016/j.bbi.2012.09.013. [PMID] 23078985.
2013
AAV-mediated gene therapy in the guanylate cyclase (RetGC1/RetGC2) double knockout mouse model of Leber congenital amaurosis.
Human gene therapy. 24(2):189-202 [DOI] 10.1089/hum.2012.193. [PMID] 23210611.
2012
Usefulness of preclinical models for assessing the efficacy of late-life interventions for sarcopenia.
The journals of gerontology. Series A, Biological sciences and medical sciences. 67(1):17-27 [DOI] 10.1093/gerona/glr042. [PMID] 21636833.
2012
Session III: Mechanisms of age-related cognitive change and targets for intervention: inflammatory, oxidative, and metabolic processes.
The journals of gerontology. Series A, Biological sciences and medical sciences. 67(7):754-9 [DOI] 10.1093/gerona/gls112. [PMID] 22570133.
2012
Role of estrogen receptor alpha and beta expression and signaling on cognitive function during aging.
Hippocampus. 22(4):656-69 [DOI] 10.1002/hipo.20935. [PMID] 21538657.
2012
Muscleblind-like 2-mediated alternative splicing in the developing brain and dysregulation in myotonic dystrophy.
Neuron. 75(3):437-50 [DOI] 10.1016/j.neuron.2012.05.029. [PMID] 22884328.
2012
Influence of viral vector-mediated delivery of superoxide dismutase and catalase to the hippocampus on spatial learning and memory during aging.
Antioxidants & redox signaling. 16(4):339-50 [DOI] 10.1089/ars.2011.4054. [PMID] 21942371.
2012
Influence of late-life exposure to environmental enrichment or exercise on hippocampal function and CA1 senescent physiology.
Neurobiology of aging. 33(4):828.e1-17 [DOI] 10.1016/j.neurobiolaging.2011.06.023. [PMID] 21820213.
2012
Increasing hippocampal estrogen receptor alpha levels via viral vectors increases MAP kinase activation and enhances memory in aging rats in the absence of ovarian estrogens.
PloS one. 7(12) [DOI] 10.1371/journal.pone.0051385. [PMID] 23240018.
2012
Characterizing cognitive aging in humans with links to animal models.
Frontiers in aging neuroscience. 4 [DOI] 10.3389/fnagi.2012.00021. [PMID] 22988439.
2012
Dissecting the age-related decline on spatial learning and memory tasks in rodent models: N-methyl-D-aspartate receptors and voltage-dependent Ca2+ channels in senescent synaptic plasticity.
Progress in neurobiology. 96(3):283-303 [DOI] 10.1016/j.pneurobio.2012.01.007. [PMID] 22307057.
2012
Characterizing cognitive aging of working memory and executive function in animal models.
Frontiers in aging neuroscience. 4 [DOI] 10.3389/fnagi.2012.00019. [PMID] 22988438.
2012
Characterizing cognitive aging of spatial and contextual memory in animal models.
Frontiers in aging neuroscience. 4 [DOI] 10.3389/fnagi.2012.00012. [PMID] 22988436.
2012
Challenges and opportunities in characterizing cognitive aging across species.
Frontiers in aging neuroscience. 4 [DOI] 10.3389/fnagi.2012.00033. [PMID] 23189053.
2012
Challenges and opportunities for characterizing cognitive aging across species.
Frontiers in aging neuroscience. 4 [DOI] 10.3389/fnagi.2012.00006. [PMID] 22988434.
2012
Behavioral model for assessing cognitive decline.
Methods in molecular biology (Clifton, N.J.). 829:145-53 [DOI] 10.1007/978-1-61779-458-2_8. [PMID] 22231811.
2012
Enhanced expression of Pctk1, Tcf12 and Ccnd1 in hippocampus of rats: Impact on cognitive function, synaptic plasticity and pathology.
Neurobiology of learning and memory. 97(1):69-80 [DOI] 10.1016/j.nlm.2011.09.006. [PMID] 21982980.
2011
Altered behavior in experimental cortical dysplasia.
Epilepsia. 52(12):2293-303 [DOI] 10.1111/j.1528-1167.2011.03267.x. [PMID] 21933180.
2011
Differential effects of enalapril and losartan on body composition and indices of muscle quality in aged male Fischer 344 × Brown Norway rats.
Age (Dordrecht, Netherlands). 33(2):167-83 [DOI] 10.1007/s11357-010-9196-y. [PMID] 21153712.
2011
Gene expression in the hippocampus: regionally specific effects of aging and caloric restriction.
Mechanisms of ageing and development. 132(1-2):8-19 [DOI] 10.1016/j.mad.2010.10.006. [PMID] 21055414.
2011
Lifelong caloric restriction prevents age-induced oxidative stress in the sympathoadrenal system of Fischer 344 x Brown Norway rats.
Biochemical and biophysical research communications. 408(3):454-8 [DOI] 10.1016/j.bbrc.2011.04.051. [PMID] 21527245.
2010
Intracellular redox state alters NMDA receptor response during aging through Ca2+/calmodulin-dependent protein kinase II.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 30(5):1914-24 [DOI] 10.1523/JNEUROSCI.5485-09.2010. [PMID] 20130200.
2010
Redox sensitive calcium stores underlie enhanced after hyperpolarization of aged neurons: role for ryanodine receptor mediated calcium signaling.
Journal of neurophysiology. 104(5):2586-93 [DOI] 10.1152/jn.00577.2010. [PMID] 20884759.
2010
Aging alters the expression of genes for neuroprotection and synaptic function following acute estradiol treatment.
Hippocampus. 20(9):1047-60 [DOI] 10.1002/hipo.20703. [PMID] 19790252.
2010
PHLPP1 splice variants differentially regulate AKT and PKCα signaling in hippocampal neurons: characterization of PHLPP proteins in the adult hippocampus.
Journal of neurochemistry. 115(4):941-55 [DOI] 10.1111/j.1471-4159.2010.06984.x. [PMID] 20819118.
2009
Comparison of lifelong and late life exercise on oxidative stress in the cerebellum.
Neurobiology of aging. 30(6):903-9 [PMID] 17976863.
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2009
Estrogen effects on cognition and hippocampal transcription in middle-aged mice.
Neurobiology of aging. 30(6):932-45 [PMID] 17950954.
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2009
Fragile X mental retardation protein replacement restores hippocampal synaptic function in a mouse model of fragile X syndrome.
Gene therapy. 16(9):1122-9 [DOI] 10.1038/gt.2009.83. [PMID] 19571888.
2009
Influence of calorie restriction on measures of age-related cognitive decline: role of increased physical activity.
The journals of gerontology. Series A, Biological sciences and medical sciences. 64(8):850-9 [DOI] 10.1093/gerona/glp060. [PMID] 19420296.
2009
Intermittent fasting alleviates the neuropathic phenotype in a mouse model of Charcot-Marie-Tooth disease.
Neurobiology of disease. 34(1):146-54 [PMID] 19320048.
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2009
Regional Health and Function in the hippocampus: Evolutionary compromises for a critical brain region.
Bioscience hypotheses. 2(4):245-251 [PMID] 20161206.
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2009
Regional hippocampal differences in AKT survival signaling across the lifespan: implications for CA1 vulnerability with aging.
Cell death and differentiation. 16(3):439-48 [DOI] 10.1038/cdd.2008.171. [PMID] 19039330.
2009
Susceptibility to Calcium Dysregulation during Brain Aging.
Frontiers in aging neuroscience. 1 [DOI] 10.3389/neuro.24.002.2009. [PMID] 20552053.
2008
AAV-mediated gene therapy for retinal degeneration in the rd10 mouse containing a recessive PDEbeta mutation.
Investigative ophthalmology & visual science. 49(10):4278-83 [DOI] 10.1167/iovs.07-1622. [PMID] 18586879.
2008
Viral vector-mediated delivery of estrogen receptor-alpha to the hippocampus improves spatial learning in estrogen receptor-alpha knockout mice.
Molecular therapy : the journal of the American Society of Gene Therapy. 16(9):1587-93 [DOI] 10.1038/mt.2008.140. [PMID] 18594506.
2007
Shift in induction mechanisms underlies an age-dependent increase in DHPG-induced synaptic depression at CA3 CA1 synapses.
Journal of neurophysiology. 98(5):2729-36 [PMID] 17898145.
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2007
Curcumin reverses impaired hippocampal neurogenesis and increases serotonin receptor 1A mRNA and brain-derived neurotrophic factor expression in chronically stressed rats.
Brain research. 1162:9-18 [PMID] 17617388.
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2007
Susceptibility to induction of long-term depression is associated with impaired memory in aged Fischer 344 rats.
Neurobiology of learning and memory. 87(4):522-35 [PMID] 17276704.
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2007
Calcium homeostasis and modulation of synaptic plasticity in the aged brain.
Aging cell. 6(3):319-25 [PMID] 17517041.
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2007
Aging effects on the limits and stability of long-term synaptic potentiation and depression in rat hippocampal area CA1.
Journal of neurophysiology. 98(2):594-601 [PMID] 17553951.
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2007
Environmental enrichment decreases the afterhyperpolarization in senescent rats.
Brain research. 1130(1):103-7 [PMID] 17169341.
View on: PubMed
2006
Gene therapy restores vision-dependent behavior as well as retinal structure and function in a mouse model of RPE65 Leber congenital amaurosis.
Molecular therapy : the journal of the American Society of Gene Therapy. 13(3):565-72 [PMID] 16223604.
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2006
Biological markers of age-related memory deficits: treatment of senescent physiology.
CNS drugs. 20(2):153-66 [PMID] 16478290.
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2005
Interaction of rapid signal transduction cascades and gene expression in mediating estrogen effects on memory over the life span.
Frontiers in neuroendocrinology. 26(2):51-64 [PMID] 16023185.
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2005
Intracellular calcium stores contribute to increased susceptibility to LTD induction during aging.
Brain research. 1031(1):125-8 [PMID] 15621020.
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2005
Prodynorphin knockout mice demonstrate diminished age-associated impairment in spatial water maze performance.
Behavioural brain research. 161(2):254-62 [PMID] 15922052.
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2004
Enhanced long-term potentiation during aging is masked by processes involving intracellular calcium stores.
Journal of neurophysiology. 91(6):2437-44 [PMID] 14762159.
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2003
Interaction of age and chronic estradiol replacement on memory and markers of brain aging.
Neurobiology of aging. 24(6):839-52 [PMID] 12927766.
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2003
The neurotoxicity induced by ethanol withdrawal in mature organotypic hippocampal slices might involve cross-talk between metabotropic glutamate type 5 receptors and N-methyl-D-aspartate receptors.
Alcoholism, clinical and experimental research. 27(11):1724-35 [PMID] 14634487.
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2003
Gene microarrays in hippocampal aging: statistical profiling identifies novel processes correlated with cognitive impairment.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 23(9):3807-19 [PMID] 12736351.
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2002
17beta-estradiol benzoate decreases the AHP amplitude in CA1 pyramidal neurons.
Journal of neurophysiology. 88(2):621-6 [PMID] 12163515.
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2002
Calcineurin as a potential contributor in estradiol regulation of hippocampal synaptic function.
Neuroscience. 113(1):89-97 [PMID] 12123687.
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2002
Calcium dysregulation in the aging brain.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. 8(4):297-301 [PMID] 12194497.
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2002
Regulation of synaptic plasticity in memory and memory decline with aging.
Progress in brain research. 138:283-303 [PMID] 12432775.
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2001
Mechanism for increased hippocampal synaptic strength following differential experience.
Journal of neurophysiology. 85(4):1377-83 [PMID] 11287462.
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2001
Examination of estradiol effects on the rapid estradiol mediated increase in hippocampal synaptic transmission in estrogen receptor alpha knockout mice.
Neuroscience letters. 309(3):207-9 [PMID] 11514077.
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2001
Calcineurin links Ca2+ dysregulation with brain aging.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 21(11):4066-73 [PMID] 11356894.
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2000
Receptor blockade reveals a correspondence between hippocampal-dependent behavior and experience-dependent synaptic enhancement.
Brain research. 871(1):39-43 [PMID] 10882780.
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2000
Novel effects of estradiol and estrogen receptor alpha and beta on cognitive function.
Brain research. 883(2):258-64 [PMID] 11074057.
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1999
MK-801 improves retention in aged rats: implications for altered neural plasticity in age-related memory deficits.
Neurobiology of learning and memory. 71(2):194-206 [PMID] 10082639.
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1999
Sex with knockout models: behavioral studies of estrogen receptor alpha.
Brain research. 835(1):80-90 [PMID] 10448199.
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1999
Involvement of hippocampal synaptic plasticity in age-related memory decline.
Brain research. Brain research reviews. 30(3):236-49 [PMID] 10567726.
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1998
Alterations in the balance of protein kinase/phosphatase activities parallel reduced synaptic strength during aging.
Journal of neurophysiology. 80(3):1567-70 [PMID] 9744962.
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1998
AMPA receptor properties in adult rat hippocampus following environmental enrichment.
Brain research. 799(1):16-25 [PMID] 9666061.
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1998
GABA(b) receptors differentially regulate hippocampal CA1 excitatory synaptic transmission across postnatal development in the rat.
Neuroscience letters. 248(2):138-40 [PMID] 9654362.
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1998
On slices, synaptosomes and dissociated neurones to study in vitro ageing physiology.
Trends in neurosciences. 21(7):286-7 [PMID] 9683319.
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1998
Reversal of age-related alterations in synaptic plasticity by blockade of L-type Ca2+ channels.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 18(9):3171-9 [PMID] 9547225.
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1998
Sex differences in the activational effect of ERalpha on spatial learning.
Hormones and behavior. 34(2):163-70 [PMID] 9799626.
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1998
Late developmental changes in the ability of adenosine A1 receptors to regulate synaptic transmission in the hippocampus.
Brain research. Developmental brain research. 105(1):137-9 [PMID] 9497087.
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1997
Age-associated changes in Ca(2+)-dependent processes: relation to hippocampal synaptic plasticity.
Hippocampus. 7(6):602-12 [PMID] 9443057.
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1997
Development of metabotropic glutamate receptor-mediated synaptic inhibition.
Neuroreport. 8(13):2919-24 [PMID] 9376531.
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1997
Insensitivity of the hippocampus to environmental stimulation during postnatal development.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 17(20):7967-73 [PMID] 9315914.
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1996
Mechanism of altered synaptic strength due to experience: relation to long-term potentiation.
Brain research. 736(1-2):243-50 [PMID] 8930330.
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1996
Increased susceptibility to induction of long-term depression and long-term potentiation reversal during aging.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 16(17):5382-92 [PMID] 8757251.
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1996
Age and stress history effects on spatial performance in a swim task in Fischer-344 rats.
Neurobiology of learning and memory. 66(1):1-10 [PMID] 8661246.
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1995
Developmental increase in CA3-CA1 presynaptic function in the hippocampal slice.
Journal of neurophysiology. 73(5):1821-8 [PMID] 7623083.
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1994
Persistent increase of hippocampal presynaptic axon excitability after repetitive electrical stimulation: dependence on N-methyl-D-aspartate receptor activity, nitric-oxide synthase, and temperature.
Proceedings of the National Academy of Sciences of the United States of America. 91(11):4830-4 [PMID] 7515179.
View on: PubMed
1992
Acetylcholine modulates averaged sensory evoked responses and perforant path evoked field potentials in the rat dentate gyrus.
Brain research. 587(1):95-101 [PMID] 1525653.
View on: PubMed
1992
Region-specific age effects on AMPA sensitivity: electrophysiological evidence for loss of synaptic contacts in hippocampal field CA1.
Hippocampus. 2(4):457-68 [PMID] 1284976.
View on: PubMed
1991
Increase in perforant path quantal size in aged F-344 rats.
Neurobiology of aging. 12(5):441-8 [PMID] 1770978.
View on: PubMed
1991
Long-term enhancement of CA1 synaptic transmission is due to increased quantal size, not quantal content.
Hippocampus. 1(1):79-91 [PMID] 1669344.
View on: PubMed
1991
Specificity of functional changes during normal brain aging.
Annals of the New York Academy of Sciences. 640:80-5 [PMID] 1776764.
View on: PubMed
1989
Effects of delta-9-tetrahydrocannabinol on sensory evoked hippocampal activity in the rat: principal components analysis and sequential dependency.
The Journal of pharmacology and experimental therapeutics. 251(3):870-7 [PMID] 2557421.
View on: PubMed
1989
Spatial selectivity of rat hippocampal neurons: dependence on preparedness for movement.
Science (New York, N.Y.). 244(4912):1580-2 [PMID] 2740902.
View on: PubMed
1988
Control of sensory activation of granule cells in the fascia dentata by extrinsic afferents: septal and entorhinal inputs.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 8(10):3869-78 [PMID] 3193182.
View on: PubMed
1987
Sequential dependencies regulate sensory evoked responses of single units in the rat hippocampus.
Brain research. 408(1-2):86-96 [PMID] 3594233.
View on: PubMed
1986
delta 9-Tetrahydrocannabinol differentially affects sensory-evoked potentials in the rat dentate gyrus.
The Journal of pharmacology and experimental therapeutics. 239(3):936-40 [PMID] 3025423.
View on: PubMed
1986
Effects of delta 9-tetrahydrocannabinol on sensory-evoked discharges of granule cells in the dentate gyrus of behaving rats.
The Journal of pharmacology and experimental therapeutics. 239(3):941-5 [PMID] 3025424.
View on: PubMed
1985
Sequence-related changes in sensory-evoked potentials in the dentate gyrus: a mechanism for item-specific short-term information storage in the hippocampus.
Behavioral and neural biology. 44(2):201-12 [PMID] 4062774.
View on: PubMed

Grants

May 2020 ACTIVE
Biobehavioral basis of knee osteoarthritis pain
Role:
Funding: NATL INST OF HLTH NIA
Jul 2018 ACTIVE
Estrogen and cognition over the lifespan
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Apr 2017 ACTIVE
University of Florida Claude D. Pepper Older Americans Independence Center (OAIC)
Role: Project Manager
Funding: NATL INST OF HLTH NIA
May 2016 ACTIVE
Systemic inflammation in regulating the onset and progression of brain aging
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Apr 2016 – Mar 2017
Claude D Pepper Older Americans Independence Center
Role: Project Manager
Funding: NATL INST OF HLTH NIA
Sep 2015 – Apr 2020
Systemic inflammation in regulating the onset and progression of brain aging
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Sep 2015 – Feb 2019
Targeting the Chaperone Pathway for Myelin Repair in Hereditary Neuropathies
Role:
Funding: NATL INST OF HLTH NINDS
Aug 2015 ACTIVE
Molecular Genetic Characterization of SCA8
Role:
Funding: NATL INST OF HLTH NINDS
Apr 2015 – Mar 2016
Claude D. Pepper Older Americans Independence Center
Role: Project Manager
Funding: NATL INST OF HLTH NIA
Sep 2014 – Apr 2019
Signaling cascades and memory deficits during aging
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Aug 2011 – May 2017
Estrogen and cognition over the lifespan
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Nov 2009 ACTIVE
Medical Research of the Brain
Role: Principal Investigator
Funding: UF FOU

Teaching Profile

Courses Taught
2014-2019
GMS6022 Principles of Neuroscience II: Cellular and Molecular Neuroscience
2018
GMS6052 Ion Channels of Excitable Membranes
2018
GMS7980 Research for Doctoral Dissertation
2018
GMS7979 Advanced Research
2018
BME7980 Research for Doctoral Dissertation
2013-2015
GMS6417 Integrative Aging Physiology
2015
GMS6063 Mechanisms of Aging
2015
GMS7794 Neuroscience Seminar
2007-2009
GMS6029 Brain Journal Club

Contact Details

Phones:
Business:
(352) 273-0033
Emails:
Business:
foster1@ufl.edu