Edgardo Rodriguez

Edgardo Rodriguez

Assistant Professor

Department: MD-PHARMACOLOGY / THERAPEUTICS
Business Phone: (352) 294-5781
Business Email: edrod@ufl.edu

Publications

2020
γ-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse γ-secretase modulators do not.
Alzheimer's research & therapy. 12(1) [DOI] 10.1186/s13195-020-00622-5. [PMID] 32430033.
2020
5’UTR-mediated regulation of Ataxin-1 expression.
Neurobiology of disease. 134 [DOI] 10.1016/j.nbd.2019.104564. [PMID] 31381977.
2019
Individual and combined presenilin 1 and 2 knockouts reveal that both have highly overlapping functions in HEK293T cells.
The Journal of biological chemistry. 294(29):11276-11285 [DOI] 10.1074/jbc.RA119.008041. [PMID] 31167792.
2019
A novel proteotoxic combination therapy for EGFR+ and HER2+ cancers.
Oncogene. 38(22):4264-4282 [DOI] 10.1038/s41388-019-0717-6. [PMID] 30718919.
2008
Unexpected Off-Targeting Effects of Anti-Huntingtin Ribozymes and Sirna in Vivo
Neurobiology of Disease. 29(3):446-455 [DOI] 10.1016/j.nbd.2007.11.003. [PMID] 18166484.
2008
Sustained Striatal Ciliary Neurotrophic Factor Expression Negatively Affects Behavior and Gene Expression in Normal and R6/1 Mice
Journal of Neuroscience Research. 86(8):1748-1757 [DOI] 10.1002/jnr.21636. [PMID] 18293418.
2004
Dobutamine-related asthma in a patient awaiting cardiac transplantation: the eosinophilic dilemma.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 23(2):260-1 [PMID] 14761776.
View on: PubMed

Grants

Aug 2015 – Jul 2018
Somatic inactivation of the SNCA locus: a new approach to the understanding and treatment of Parkinson's Disease
Role: Principal Investigator
Funding: NATL INST OF HLTH NINDS
Jul 2015 – Jun 2018
Towards a knockdown therapy for tauopathy
Role: Project Manager
Funding: BRIGHTFOCUS FOU
Sep 2014 – Mar 2017
Analysis of MiRNA Expression
Role: Principal Investigator
Funding: NATL INST OF HLTH NINDS

Patents

Published June 2003
Production of Pseudotyped Recombinant AAV Virions
#2007-0015238-A1
Issued August 2006
Production of Pseudotyped Recombinant AAV Virions
#7,094,604

Teaching Profile

Courses Taught
2016,2020
GMS6251 Molecular Therapy I ? Vectors and Molecular Mechanisms
2017-2020
DEN6262 Prin of Pharmacology
2018
GMS6560 Molecules to Man: Past, Present and Future Therapeutic Strategies for Disease
2018
GMS7980 Research for Doctoral Dissertation
2018
GMS6009 Principles of Drug Action and Therapeutics
2017
GMS6847 Translational Research and Therapeutics: Bench, Bedside, Community, & Policy
2015
GMS6029 Brain Journal Club

Contact Details

Phones:
Business:
(352) 294-5781
Emails:
Business:
edrod@ufl.edu