Rebecca L Wallings

Rebecca L Wallings,

POSTDOC ASO

Department: Department of Neuroscience
Business Phone: (352) 627-9200
Business Email: rebeccawallings@ufl.edu

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0003-0947-4459

Publications

2022
Inflammation and immune dysfunction in Parkinson disease.
Nature reviews. Immunology. 22(11):657-673 [DOI] 10.1038/s41577-022-00684-6. [PMID] 35246670.
2022
WHOPPA Enables Parallel Assessment of Leucine-Rich Repeat Kinase 2 and Glucocerebrosidase Enzymatic Activity in Parkinson’s Disease Monocytes.
Frontiers in cellular neuroscience. 16 [DOI] 10.3389/fncel.2022.892899. [PMID] 35755775.
2021
Gene therapy restores dopamine transporter expression and ameliorates pathology in iPSC and mouse models of infantile parkinsonism
Science Translational Medicine. 13(594) [DOI] 10.1126/scitranslmed.aaw1564. [PMID] 34011628.
2020
Linking mitochondria to the immune response
eLife. 9 [DOI] 10.7554/elife.56214.
2020
LRRK2 at the Interface Between Peripheral and Central Immune Function in Parkinson’s.
Frontiers in neuroscience. 14 [DOI] 10.3389/fnins.2020.00443. [PMID] 32508566.
2019
LRRK2 interacts with the vacuolar-type H+-ATPase pump a1 subunit to regulate lysosomal function
Human Molecular Genetics. 28(16):2696-2710 [DOI] 10.1093/hmg/ddz088. [PMID] 31039583.
2019
LRRK2 regulation of immune-pathways and inflammatory disease.
Biochemical Society transactions. 47(6):1581-1595 [DOI] 10.1042/BST20180463. [PMID] 31769472.
2019
Lysosomal Dysfunction at the Centre of Parkinson’s Disease and Frontotemporal Dementia/Amyotrophic Lateral Sclerosis.
Trends in neurosciences. 42(12):899-912 [DOI] 10.1016/j.tins.2019.10.002. [PMID] 31704179.
2016
LRRK2 BAC transgenic rats develop progressive, L-DOPA-responsive motor impairment, and deficits in dopamine circuit function.
Human molecular genetics. 25(5):951-63 [DOI] 10.1093/hmg/ddv628. [PMID] 26744332.
2015
Cellular processes associated with LRRK2 function and dysfunction.
The FEBS journal. 282(15):2806-26 [DOI] 10.1111/febs.13305. [PMID] 25899482.

Grants

Jul 2021 ACTIVE
The role of the peripheral immune-system in FTD-GRN; increasing understanding for future therapeutic target development
Role: Principal Investigator
Funding: BRIGHTFOCUS FOU

Contact Details

Phones:
Business:
(352) 627-9200
Emails:
Addresses:
Business Mailing:
PO Box 100244
GAINESVILLE FL 32610
Business Street:
1149 NEWELL DR
MCKNIGHT BRAIN INSTITUTE
GAINESVILLE FL 326103011